Description
Antibody Name: | IL32 Antibody (PACO46378) |
Antibody SKU: | PACO46378 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Interleukin-32 protein (31-234AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO46378 at dilution of 1:100. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO46378 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
Background: | Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-α and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. |
Synonyms: | Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor), IL32, NK4 TAIF |
UniProt Protein Function: | IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: extracellular space; membrane Molecular Function:protein binding; cytokine activity Biological Process: defense response; immune response; cell adhesion |
NCBI Summary: | This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
UniProt Code: | P24001 |
NCBI GenInfo Identifier: | 61658632 |
NCBI Gene ID: | 9235 |
NCBI Accession: | NP_001012650.1 |
UniProt Related Accession: | P24001 |
Molecular Weight: | |
NCBI Full Name: | interleukin-32 isoform B |
NCBI Synonym Full Names: | interleukin 32 |
NCBI Official Symbol: | IL32 |
NCBI Official Synonym Symbols: | NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma |
NCBI Protein Information: | interleukin-32 |
UniProt Protein Name: | Interleukin-32 |
UniProt Synonym Protein Names: | Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor |
Protein Family: | Interleukin |
UniProt Gene Name: | IL32 |
UniProt Entry Name: | IL32_HUMAN |
Antibodies | ELISA Kits |
IL32 Antibody (PACO00961) | Human IL-32 ELISA Kit (HUFI01624) |
IL32 Antibody (PACO09935) | Human IL-32 CLIA Kit (HUES00175) |
Human IL-32 ELISA Kit (HUES01473) | |
Human IL-32 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |