IL32 Antibody (PACO00961)
- SKU:
- PACO00961
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IL32 Antibody |
| Antibody SKU: | PACO00961 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human IL-32. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | IL32; NK4; TAIF; Interleukin-32; IL-32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor |
| UniProt Protein Function: | IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: extracellular space; membrane Molecular Function:protein binding; cytokine activity Biological Process: defense response; immune response; cell adhesion |
| NCBI Summary: | This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P24001 |
| NCBI GenInfo Identifier: | 61658632 |
| NCBI Gene ID: | 9235 |
| NCBI Accession: | NP_001012650.1 |
| UniProt Related Accession: | P24001 |
| Molecular Weight: | |
| NCBI Full Name: | interleukin-32 isoform B |
| NCBI Synonym Full Names: | interleukin 32 |
| NCBI Official Symbol: | IL32 |
| NCBI Official Synonym Symbols: | NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma |
| NCBI Protein Information: | interleukin-32 |
| UniProt Protein Name: | Interleukin-32 |
| UniProt Synonym Protein Names: | Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL32 |
| UniProt Entry Name: | IL32_HUMAN |
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