Description
| Product Name: | IL23R Monoclonal Antibody |
| Product Code: | CAB22561 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58334 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Raji, RAW264.7, Mouse thymus |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-629 of human IL23R (NP_653302.2). |
| Sequence: | KPPVD SLDSG NNPRL QKHPN FAFSV SSVNS LSNTI FLGEL SLILN QGECS SPDIQ NSVEE ETTML LENDS PSETI PEQTL LPDEF VSCLG IVNEE LPSIN TYFPQ NILES HFNRI SLLEK |
| Synonyms: | PSORS7 |
| Calculated MW: | 72kDa |
| Observed MW: | 72kDa |