Description
Product Name: | IL23R Monoclonal Antibody |
Product Code: | CAB22561 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58334 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, Raji, RAW264.7, Mouse thymus |
Cellular Location: | Cell membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-629 of human IL23R (NP_653302.2). |
Sequence: | KPPVD SLDSG NNPRL QKHPN FAFSV SSVNS LSNTI FLGEL SLILN QGECS SPDIQ NSVEE ETTML LENDS PSETI PEQTL LPDEF VSCLG IVNEE LPSIN TYFPQ NILES HFNRI SLLEK |
Synonyms: | PSORS7 |
Calculated MW: | 72kDa |
Observed MW: | 72kDa |