IL2 Monoclonal Antibody (CAB22200)
- SKU:
- CAB22200
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL2 Monoclonal Antibody |
| Product Code: | CAB22200 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55614 |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant Mouse IL-2 protein |
| Cellular Location: | extracellular space |
Enables cytokine activity and interleukin-2 receptor binding activity. Involved in negative regulation of T-helper 17 cell differentiation. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of macromolecule metabolic process; and regulation of lymphocyte activation. Located in extracellular space. Is expressed in liver; omental bursa; thymus; and thymus primordium. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in several diseases, including Takayasu's arteritis; auditory system disease (multiple); autoimmune disease (multiple); carcinoma (multiple); and neurodegenerative disease (multiple). Orthologous to human IL2 (interleukin 2).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-169 of mouse IL2 (NP_032392.1). |
| Sequence: | APTSS STSSS TAEAQ QQQQQ QQQQQ QHLEQ LLMDL QELLS RMENY RNLKL PRMLT FKFYL PKQAT ELKDL QCLED ELGPL RHVLD LTQSK SFQLE DAENF ISNIR VTVVK LKGSD NTFEC QFDDE SATVV DFLRR WIAFC QSIIS TSPQ |
| Synonyms: | Il-2 |
| Calculated MW: | 19kDa |
| Observed MW: | 22kDa |
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