IL18R1/IL-18 R alpha Monoclonal Antibody (CAB22369)
- SKU:
- CAB22369
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL18R1/IL-18 R alpha Monoclonal Antibody |
| Product Code: | CAB22369 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52215 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant Human IL18R1 Protein |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 141-320 of human IL18R1/IL-18 R alpha (NP_003846.1). |
| Sequence: | ENSYY QTLVN STSLY KNCKK LLLEN NKNPT IKKNA EFEDQ GYYSC VHFLH HNGKL FNITK TFNIT IVEDR SNIVP VLLGP KLNHV AVELG KNVRL NCSAL LNEED VIYWM FGEEN GSDPN IHEEK EMRIM TPEGK WHASK VLRIE NIGES NLNVL YNCTV ASTGG TDTKS FILVR KADMA |
| Synonyms: | CD218a, IL18RA, IL1RRP, CDw218a, IL-1Rrp, IL-18Ralpha, IL18Ralpha2, IL-18R-alpha |
| Calculated MW: | 62kDa |
| Observed MW: | 80-105kDa |
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