IL18R1/IL-18 R alpha Monoclonal Antibody (CAB21208)

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SKU:
CAB21208
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:IL18R1/IL-18 R alpha Monoclonal Antibody
Product Code:CAB21208
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC52216
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Recombinant Human IL18R1 Protein
Cellular Location:Membrane, Single-pass type I membrane protein

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 141-320 of human IL18R1/IL-18 R alpha (NP_003846.1).
Sequence:ENSYY QTLVN STSLY KNCKK LLLEN NKNPT IKKNA EFEDQ GYYSC VHFLH HNGKL FNITK TFNIT IVEDR SNIVP VLLGP KLNHV AVELG KNVRL NCSAL LNEED VIYWM FGEEN GSDPN IHEEK EMRIM TPEGK WHASK VLRIE NIGES NLNVL YNCTV ASTGG TDTKS FILVR KADMA
Synonyms:CD218a, IL18RA, IL1RRP, CDw218a, IL-1Rrp, IL-18Ralpha, IL18Ralpha2, IL-18R-alpha
Calculated MW:62kDa
Observed MW:95kDa
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