Cell Biology Antibodies 15
IL18 Rabbit pAb (CAB20473)
- SKU:
- CAB20473
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
Description
Antibody Name: | IL18 Rabbit pAb (CAB20473) |
Antibody SKU: | CAB20473 |
Antibody Size: | 50uL, 100uL |
Application: | WB, IHC |
Reactivity: | Human, Mouse, Rta |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of Mouse IL18. |
Application: | WB, IHC |
Recommended Dilution: | WB 1:500 - 1:2000, IHC 1:50-1:200 |
Reactivity: | Human, Mouse, Rta |
Positive Samples: | RAW264.7, Mouse spleen, Rat brain |
Immunogen: | Recombinant protein of Mouse IL18. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | |
Gene ID: | 16173 |
Uniprot: | P70380 |
Cellular Location: | |
Calculated MW: | 22kDa |
Observed MW: | 22kDa/18kDa |
Synonyms: | Ig, Il-, Igif, Il-18 |
Background: |
UniProt Protein Function: | IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. |
UniProt Protein Details: | Protein type:Cytokine Cellular Component: extracellular space; apical plasma membrane; cytoplasm; extracellular region Molecular Function:cytokine activity Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of smooth muscle cell migration; positive regulation of activated T cell proliferation; positive regulation of interleukin-8 production; positive regulation of superoxide release; positive regulation of neuron apoptosis; lipopolysaccharide-mediated signaling pathway; angiogenesis; inflammatory response; positive regulation of interleukin-17 production; regulation of cell adhesion; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; positive regulation of tumor necrosis factor production; sleep; positive regulation of chemokine production; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; detection of mechanical stimulus involved in sensory perception of pain; positive regulation of interferon-gamma production; induction of apoptosis via death domain receptors; response to hypoxia; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation |
UniProt Code: | P70380 |
NCBI GenInfo Identifier: | 3219810 |
NCBI Gene ID: | 16173 |
NCBI Accession: | P70380.2 |
UniProt Related Accession: | P70380 |
Molecular Weight: | |
NCBI Full Name: | Interleukin-18 |
NCBI Synonym Full Names: | interleukin 18 |
NCBI Official Symbol: | Il18 |
NCBI Official Synonym Symbols: | Igif; Il-18 |
NCBI Protein Information: | interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor |
UniProt Protein Name: | Interleukin-18 |
UniProt Synonym Protein Names: | Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma |
Protein Family: | Interleukin |
UniProt Gene Name: | Il18 |
UniProt Entry Name: | IL18_MOUSE |