IL18 Monoclonal Antibody (CAB23999)

(No reviews yet) Write a Review
SKU:
CAB23999
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:IL18 Monoclonal Antibody
Product Code:CAB23999
Reactivity:Human, Mouse
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC53990
Reactivity:Human, Mouse
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:2000-1:10000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:DU145, HeLa
Cellular Location:Secreted

The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 37-193 of human IL18 (NP_001553.1).
Sequence:YFGKL ESKLS VIRNL NDQVL FIDQG NRPLF EDMTD SDCRD NAPRT IFIIS MYKDS QPRGM AVTIS VKCEK ISTLS CENKI ISFKE MNPPD NIKDT KSDII FFQRS VPGHD NKMQF ESSSY EGYFL ACEKE RDLFK LILKK EDELG DRSIM FTVQN ED
Synonyms:IGIF, IL-18, IL-1g, IL1F4
Calculated MW:22kDa
Observed MW:22kDa
View AllClose

0 Reviews

View AllClose

Related Products

IL18 Monoclonal Antibody (CAB21950)

IL18 Monoclonal Antibody (CAB21950)

IL18 Monoclonal Antibody (CAB21950)The product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!