IL17D Antibody (PACO07421)
- SKU:
- PACO07421
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IL17D Antibody (PACO07421) |
| Antibody SKU: | PACO07421 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:10000-1:20000, IHC-p:1:50-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide from human protein at AA range: 141-190 |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100. |
 | Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100. |
 | Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100. |
| Synonyms: | Interleukin-17D (IL-17D) (Interleukin-27) (IL-27) |
| UniProt Protein Function: | IL17D: Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells. Belongs to the IL-17 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cytokine Chromosomal Location of Human Ortholog: 13q11 Cellular Component: extracellular space Molecular Function:cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding Biological Process: cell surface receptor linked signal transduction; inflammatory response |
| NCBI Summary: | The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TAD2 |
| NCBI GenInfo Identifier: | 46576614 |
| NCBI Gene ID: | 53342 |
| NCBI Accession: | Q8TAD2.1 |
| UniProt Secondary Accession: | Q8TAD2,B1AM69, |
| UniProt Related Accession: | Q8TAD2 |
| Molecular Weight: | 21,893 Da |
| NCBI Full Name: | Interleukin-17D |
| NCBI Synonym Full Names: | interleukin 17D |
| NCBI Official Symbol: | IL17D |
| NCBI Official Synonym Symbols: | IL-17D |
| NCBI Protein Information: | interleukin-17D |
| UniProt Protein Name: | Interleukin-17D |
| UniProt Synonym Protein Names: | Interleukin-27 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL17D |
| UniProt Entry Name: | IL17D_HUMAN |
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