IL12B Antibody (PACO27585)

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SKU:
PACO27585
Product Type:
Antibody
Reactivity:
Sheep
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:IL12B Antibody (PACO27585)
Antibody SKU:PACO27585
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Sheep
Immunogen:Recombinant Sheep Interleukin-12 subunit β protein (23-327AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-γ by resting PBMC By similarity.Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis By similarity.
Synonyms:Interleukin-12 subunit β (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (IL-12 subunit p40), IL12B
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
UniProt Code:P68220
NCBI GenInfo Identifier:57164231
NCBI Gene ID:443472
NCBI Accession:NP_001009438.1
UniProt Secondary Accession:P68220
UniProt Related Accession:P68220
Molecular Weight:
NCBI Full Name:interleukin-12 subunit beta
NCBI Synonym Full Names:
NCBI Official Symbol:IL12B  
NCBI Official Synonym Symbols:IL-12  
NCBI Protein Information:interleukin-12 subunit beta
UniProt Protein Name:
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:
UniProt Entry Name:
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