IL10 Polyclonal Antibody (CAB20723)
- SKU:
- CAB20723
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL10 Polyclonal Antibody |
| Product Code: | CAB20723 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | extracellular space |
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-178 of mouse IL10 (NP_034678.1). |
| Sequence: | SRGQY SREDN NCTHF PVGQS HMLLE LRTAF SQVKT FFQTK DQLDN ILLTD SLMQD FKGYL GCQAL SEMIQ FYLVE VMPQA EKHGP EIKEH LNSLG EKLKT LRMRL RRCHR FLPCE NKSKA VEQVK SDFNK LQDQG VYKAM NEFDI FINCI EAYMM IKMKS |
| Synonyms: | CSIF, If2a, Il-10 |
| Calculated MW: | 21kDa |
| Observed MW: | 18kDa/21kDa |
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