IL-36 Gamma Monoclonal Antibody
- SKU:
- CAB23961
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | IL-36 Gamma Monoclonal Antibody |
| Product Code: | CAB23961 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62706 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T-IL-36 Gamma-Flag-N |
| Cellular Location: | Cytoplasm, secreted |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-169 of human IL-36 Gamma (NP_062564.1). |
| Sequence: | SMCKP ITGTI NDLNQ QVWTL QGQNL VAVPR SDSVT PVTVA VITCK YPEAL EQGRG DPIYL GIQNP EMCLY CEKVG EQPTL QLKEQ KIMDL YGQPE PVKPF LFYRA KTGRT STLES VAFPD WFIAS SKRDQ PIILT SELGK SYNTA FELNI ND |
| Synonyms: | IL36G, IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1, IL1RP2, interleukin-36 gamma |
| Calculated MW: | 14kDa/18kDa |
| Observed MW: | 19kDa |
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