IL-31 Monoclonal Antibody
- SKU:
- CAB24426
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | IL-31 Monoclonal Antibody |
| Product Code: | CAB24426 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63326 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:4000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant protein of human IL-31 |
| Cellular Location: | Secreted |
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-164 of human IL-31 (NP_001014358.1). |
| Sequence: | SHTLP VRLLR PSDDV QKIVE ELQSL SKMLL KDVEE EKGVL VSQNY TLPCL SPDAQ PPNNI HSPAI RAYLK TIRQL DNKSV IDEII EHLDK LIFQD APETN ISVPT DTHEC KRFIL TISQQ FSECM DLALK SLTSG AQQAT T |
| Synonyms: | IL-31 |
| Calculated MW: | 18kDa |
| Observed MW: | 25-30kDa |
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