Description
system_update_alt Datasheet
Product Name: | IL 1RA Antibody |
Product Sku: | CPAB0050 |
Size: | 500μg |
Host Species: | Mouse |
Immunogen: | r.Human IL-1RA |
Clone: | NYR-hIL1RA. |
Reactivity: | Human |
Applications: | Immuneprecipitation, Western Blot, ELISA |
Purification Method: | Ion exchange |
Isotype: | IgG2b |
Background: | Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Synonyms: | IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |