Description
Product Name: | IL-13 receptor alpha 1 Monoclonal Antibody |
Product Code: | CAB24286 |
Reactivity: | Human |
Applications: | Flow Cytometry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62791 |
Reactivity: | Human |
Tested Applications: | FC, ELISA |
Key Applications: | Flow Cytometry |
Recommended Dilution: | FC 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | External side of plasma membrane, Plasma membrane |
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids of human IL-13 receptor alpha 1 (NP_001551.1). |
Sequence: | TETQP PVTNL SVSVE NLCTV IWTWN PPEGA SSNCS LWYFS HFGDK QDKKI APETR RSIEV PLNER ICLQV GSQCS TNESE KPSIL VEKCI SPPEG DPESA VTELQ CIWHN LSYMK CSWLP GRNTS PDTNY TLYYW HRSLE KIHQC ENIFR EGQYF GCSFD LTKVK DSSFE QHSVQ IMVKD NAGKI KPSFN IVPLT SRVKP DPPHI KNLSF HNDDL YVQWE NPQNF ISRCL FYEVE VNNSQ TETHN VFYVQ EAKCE NPEFE RNVEN TSCFM VPGVL PDTLN TVRIR VKTNK LCYED DKLWS NWSQE MSIGK KRNST |
Synonyms: | NR4, CT19, CD213A1, IL-13Ra |
Calculated MW: | 49kDa |
Observed MW: | Refer to figures |