IL 10 Monoclonal Antibody [MI10-L2] (CPAB0347)

Name: IL 10 Monoclonal Antibody [MI10-L2] (CPAB0347)
SKU: CPAB0347
Availability: OutOfStock

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CD127/IL-7Rα Monoclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!

Purification Method:	Boric Acid precipitation/ S-Sepharose.
Isotype:	IgM
Background:	IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Synonyms:	B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.
Storage Buffer:	In lyophilized form, for long periods, store at 4ºC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20ºC.