Description
Product Name: | IL-1 alpha Monoclonal Antibody |
Product Code: | CAB22766 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58205 |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:10000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Recombinant Mouse IL-1 alpha Protein |
Cellular Location: | Nucleus, Secreted, Cytoplasm |
Enables cytokine activity and interleukin-1 receptor binding activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including cell surface receptor signaling pathway; connective tissue replacement involved in inflammatory response wound healing; and positive regulation of cytokine production. Located in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 115-270 of mouse IL-1 alpha (NP_034684.2). |
Sequence: | SAPYT YQSDL RYKLM KLVRQ KFVMN DSLNQ TIYQD VDKHY LSTTW LNDLQ QEVKF DMYAY SSGGD DSKYP VTLKI SDSQL FVSAQ GEDQP VLLKE LPETP KLITG SETDL IFFWK SINSK NYFTS AAYPE LFIAT KEQSR VHLAR GLPSM TDFQI S |
Synonyms: | Il-1a |
Calculated MW: | 31kDa |
Observed MW: | 20-25kDa |