IKZF3 Monoclonal Antibody
- SKU:
- CAB22433
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | IKZF3 Monoclonal Antibody |
| Product Code: | CAB22433 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC1755 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Rat lung |
| Cellular Location: | cytoplasm, cytosol, nucleoplasm, nucleus |
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IKZF3 (Q9UKT9). |
| Sequence: | MEDIQ TNAEL KSTQE QSVPA ESAAV LNDYS LTKSH EMENV DSGEG PANED EDIGD DSMKV KDEYS ERDEN VLKSE PMGNA EEPEI PYSYS REYNE YENIK |
| Synonyms: | AIO, IMD84, AIOLOS, ZNFN1A3 |
| Calculated MW: | 58kDa |
| Observed MW: | 50-70kDa |
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