IGSF10 Antibody (PACO14564)
- SKU:
- PACO14564
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IGSF10 Antibody (PACO14564) |
| Antibody SKU: | PACO14564 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human IGSF10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14564(IGSF10 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid, secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation. |
| Synonyms: | immunoglobulin superfamily, member 10 |
| UniProt Protein Function: | IGSF10: May be involved in the maintenance of osteochondroprogenitor cells pool. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Immunoglobulin superfamily; Secreted, signal peptide; Protein kinase, tyrosine (receptor); Kinase, protein; SecretedChromosomal Location of Human Ortholog: 3q25.1Cellular Component: extracellular regionBiological Process: ossification; multicellular organismal development; cell differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6WRI0 |
| NCBI GenInfo Identifier: | 74749492 |
| NCBI Gene ID: | 285313 |
| NCBI Accession: | Q6WRI0.1 |
| UniProt Secondary Accession: | Q6WRI0,Q86YJ9, Q8N772, Q8NA84 |
| UniProt Related Accession: | Q6WRI0 |
| Molecular Weight: | 66,741 Da |
| NCBI Full Name: | Immunoglobulin superfamily member 10 |
| NCBI Synonym Full Names: | immunoglobulin superfamily, member 10 |
| NCBI Official Symbol: | IGSF10 |
| NCBI Official Synonym Symbols: | CMF608 |
| NCBI Protein Information: | immunoglobulin superfamily member 10; calvaria mechanical force protein 608 |
| UniProt Protein Name: | Immunoglobulin superfamily member 10 |
| UniProt Synonym Protein Names: | Calvaria mechanical force protein 608; CMF608 |
| Protein Family: | Immunoglobulin superfamily |
| UniProt Gene Name: | IGSF10 |
| UniProt Entry Name: | IGS10_HUMAN |
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