IGF2BP3/IMP3 Monoclonal Antibody
- SKU:
- CAB23295
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | IGF2BP3/IMP3 Monoclonal Antibody |
| Product Code: | CAB23295 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60319 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, T-47D(Negative control), NIH/3T3, Mouse testis |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-579 of human IGF2BP3/IMP3（NP_006538.2）. |
| Sequence: | NKLYI GNLSE NAAPS DLESI FKDAK IPVSG PFLVK TGYAF VDCPD ESWAL KAIEA LSGKI ELHGK PIEVE HSVPK RQRIR KLQIR NIPPH LQWEV LDSLL VQYGV VESCE QVNTD SETAV VNVTY SSKDQ ARQAL DKLNG FQLEN FTLKV AYIPD EMAAQ QNPLQ QPRGR RGLGQ RGSSR QGSPG SVSKQ KPC |
| Synonyms: | KOC, CT98, IMP3, KOC1, IMP-3, VICKZ3 |
| Calculated MW: | 64kDa |
| Observed MW: | 70kDa |
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