Description
| Product Name: | IGF2BP1/IMP1 Polyclonal Antibody |
| Product Code: | CAB22246 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, 293F, NIH/3T3, Mouse brain, Rat kidney |
| Cellular Location: | CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, growth cone, nucleoplasm, nucleus, P-body, perinuclear region of cytoplasm |
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human IMP1 (NP_006537.3). |
| Sequence: | MNKLY IGNLN ESVTP ADLEK VFAEH KISYS GQFLV KSGYA FVDCP DEHWA MKAIE TFSGK VELQG KRLEI EHSVP KKQRS RKIQI RNIPP QLRWE VLDSL |
| Synonyms: | IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1 |
| Calculated MW: | 63kDa |
| Observed MW: | 64kDa |