Description
Product Name: | IGF2BP1/IMP1 Polyclonal Antibody |
Product Code: | CAB22246 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HepG2, 293F, NIH/3T3, Mouse brain, Rat kidney |
Cellular Location: | CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, growth cone, nucleoplasm, nucleus, P-body, perinuclear region of cytoplasm |
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human IMP1 (NP_006537.3). |
Sequence: | MNKLY IGNLN ESVTP ADLEK VFAEH KISYS GQFLV KSGYA FVDCP DEHWA MKAIE TFSGK VELQG KRLEI EHSVP KKQRS RKIQI RNIPP QLRWE VLDSL |
Synonyms: | IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1 |
Calculated MW: | 63kDa |
Observed MW: | 64kDa |