Description
| Product Name: | IGF2BP1/IMP1 Monoclonal Antibody |
| Product Code: | CAB22612 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57768 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562, Hep G2, NIH-3T3, K-562, rat kidney |
| Cellular Location: | CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, growth cone, nucleoplasm, nucleus, P-body, perinuclear region of cytoplasm |
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IGF2BP1/IMP1 (NP_006537.3). |
| Sequence: | MNKLY IGNLN ESVTP ADLEK VFAEH KISYS GQFLV KSGYA FVDCP DEHWA MKAIE TFSGK VELQG KRLEI EHSVP KKQRS RKIQI RNIPP QLRWE VLDSL |
| Synonyms: | IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1 |
| Calculated MW: | 63kDa |
| Observed MW: | 63kDa |