Description
Product Name: | IGF2 Polyclonal Antibody |
Product Code: | CAB24842 |
Reactivity: | Human, Mouse, Rat |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | IF/ICC |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | Secreted |
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 70-180 of human IGF2 (P01344). |
Sequence: | CCFRS CDLAL LETYC ATPAK SERDV STPPT VLPDN FPRYP VGKFF QYDTW KQSTQ RLRRG LPALL RARRG HVLAK ELEAF REAKR HRPLI ALPTQ DPAHG GAPPE MASNR K |
Synonyms: | IGF2, C11orf43, GRDF, IGF-II, PP9974, insulin like growth factor 2 |
Calculated MW: | 20kDa/26kDa |
Observed MW: | Refer to figures |