IFT27 Antibody (PACO41262)
- SKU:
- PACO41262
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IFT27 Antibody (PACO41262) |
| Antibody SKU: | PACO41262 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO41262 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO41262 at dilution of 1:100. |
| Background: | Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 (By similarity). |
| Synonyms: | Intraflagellar transport protein 27 homolog (Putative GTP-binding protein RAY-like) (Rab-like protein 4), IFT27, RABL4 RAYL |
| UniProt Protein Function: | RABL4: Possesses GTPase activity. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein; G protein, monomeric; G protein, monomeric, RasChromosomal Location of Human Ortholog: 22q13.1Cellular Component: ciliumMolecular Function: protein bindingBiological Process: intracellular protein transport; intraflagellar transport; smoothened signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q9BW83 |
| NCBI GenInfo Identifier: | 20178058 |
| NCBI Gene ID: | 11020 |
| NCBI Accession: | Q9BW83.1 |
| UniProt Secondary Accession: | Q9BW83,O60897 |
| UniProt Related Accession: | Q9BW83 |
| Molecular Weight: | 20,423 Da |
| NCBI Full Name: | Intraflagellar transport protein 27 homolog |
| NCBI Synonym Full Names: | intraflagellar transport 27 |
| NCBI Official Symbol: | IFT27 |
| NCBI Official Synonym Symbols: | RAYL; BBS19; RABL4 |
| NCBI Protein Information: | intraflagellar transport protein 27 homolog |
| UniProt Protein Name: | Intraflagellar transport protein 27 homolog |
| UniProt Synonym Protein Names: | Putative GTP-binding protein RAY-like; Rab-like protein 4 |
| Protein Family: | Intraflagellar transport protein |
| UniProt Gene Name: | IFT27 |
| UniProt Entry Name: | IFT27_HUMAN |
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