Description
| Antibody Name: | IFNL4 Antibody (PACO47838) |
| Antibody SKU: | PACO47838 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Interferon lambda-4 protein (34-76AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of Hela cells using PACO47838 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes. |
| Synonyms: | Interferon lambda-4 (IFN-lambda-4), IFNL4 |
| UniProt Protein Function: | IFNL4: Cytokine that may trigger an antiviral response activating the JAK-STAT pathway and up-regulating specifically some interferon-stimulated genes. Belongs to the lambda interferon family. Up-regulated by polyinosinic:polycytidylic acid (polyI:C) which mimics double-stranded hepatitis C virus. 4 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 19q13.2Cellular Component: cytoplasm; extracellular spaceMolecular Function: cytokine activityBiological Process: defense response to virus; innate immune response; regulation of T cell activation; tyrosine phosphorylation of Stat1 protein; tyrosine phosphorylation of Stat2 protein |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | K9M1U5 |
| NCBI GenInfo Identifier: | 482513660 |
| NCBI Gene ID: | 101180976 |
| NCBI Accession: | NP_001263183.2 |
| UniProt Secondary Accession: | K9M1U5,K9M1A5, K9M269, K9M2P7 |
| UniProt Related Accession: | K9M1U5 |
| Molecular Weight: | 11,992 Da |
| NCBI Full Name: | interferon lambda-4 |
| NCBI Synonym Full Names: | interferon lambda 4 (gene/pseudogene) |
| NCBI Official Symbol: | IFNL4 |
| NCBI Official Synonym Symbols: | IFNAN |
| NCBI Protein Information: | interferon lambda-4 |
| UniProt Protein Name: | Interferon lambda-4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Interferon |
| UniProt Gene Name: | IFNL4 |
| UniProt Entry Name: | IFNL4_HUMAN |
