IFNL2/IFNL3 Polyclonal Antibody
- SKU:
- CAB23437
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IFNL2/IFNL3 Polyclonal Antibody |
| Product Code: | CAB23437 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant Human IFNL3 Protein, K-562, Mouse thymus |
| Cellular Location: | Secreted |
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFNL2/IFNL3 (NP_742151.2). |
| Sequence: | MTGDC MPVLV LMAAV LTVTG AVPVA RLRGA LPDAR GCHIA QFKSL SPQEL QAFKR AKDAL EESLL LKDCK CRSRL FPRTW DLRQL QVRER PVALE AELAL |
| Synonyms: | IL28B, IL28C, IL-28B, IL-28C, IFN-lambda-3, IFN-lambda-4 |
| Calculated MW: | 22kDa |
| Observed MW: | 24kDa |
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