IFNA5 Antibody (PACO62307)
- SKU:
- PACO62307
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IFNA5 Antibody (PACO62307) |
| Antibody SKU: | PACO62307 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Interferon alpha-5 protein (52-73AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO62307 diluted at 1:100 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Produced by macrophages, IFN-α have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. |
| Synonyms: | Interferon alpha-5 (IFN-alpha-5) (Interferon alpha-61) (Interferon alpha-G) (LeIF G), IFNA5 |
| UniProt Protein Function: | IFNA5: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family.Protein type: Secreted, signal peptide; Cytokine; SecretedChromosomal Location of Human Ortholog: 9p22Cellular Component: extracellular region; extracellular spaceMolecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor bindingBiological Process: adaptive immune response; B cell differentiation; B cell proliferation; blood coagulation; cytokine and chemokine mediated signaling pathway; humoral immune response; innate immune response; natural killer cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; response to exogenous dsRNA; T cell activation during immune response |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P01569 |
| NCBI GenInfo Identifier: | 124457 |
| NCBI Gene ID: | 3442 |
| NCBI Accession: | P01569.1 |
| UniProt Secondary Accession: | P01569,Q52LX3 |
| UniProt Related Accession: | P01569 |
| Molecular Weight: | 21,942 Da |
| NCBI Full Name: | Interferon alpha-5 |
| NCBI Synonym Full Names: | interferon alpha 5 |
| NCBI Official Symbol: | IFNA5 |
| NCBI Official Synonym Symbols: | INA5; INFA5; leIF G; IFN-alphaG; IFN-alpha-5 |
| NCBI Protein Information: | interferon alpha-5 |
| UniProt Protein Name: | Interferon alpha-5 |
| UniProt Synonym Protein Names: | Interferon alpha-61; Interferon alpha-G; LeIF G |
| Protein Family: | Interferon |
| UniProt Gene Name: | IFNA5 |
| UniProt Entry Name: | IFNA5_HUMAN |
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