Description
Product Name: | IFN-beta Monoclonal Antibody |
Product Code: | CAB22740 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58590 |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:7000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Recombinant Mouse IFN-beta Protein |
Cellular Location: | Secreted |
Customer Validation: | WB(Homo sapiens) |
Enables cytokine activity and type I interferon receptor binding activity. Involved in B cell proliferation; cellular response to virus; and type I interferon signaling pathway. Acts upstream of or within several processes, including cellular response to organic cyclic compound; defense response to other organism; and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human IFN-beta (NP_034640.1) |
Sequence: | MNNRW ILHAA FLLCF STTAL SINYK QLQLQ ERTNI RKCQE LLEQL NGKIN LTYRA DFKIP MEMTE KMQKS YTAFA IQEML QNVFL VFRNN FSSTG WNETI VVRLL DELHQ QTVFL KTVLE EKQEE RLTWE MSSTA LHLKS YYWRV QRYLK LMKYN SYAWM VVRAE IFRNF LIIRR LTRNF QN |
Synonyms: | Ifb, IFNB, If1da1, IFN-beta |
Calculated MW: | 22kDa |
Observed MW: | 63kDa (C-hFc&His taged Active Recombinant Mouse IFN-beta Protein),24kDa/26kDa(Endogenous) |