IFITM5 Antibody (PACO45926)
- SKU:
- PACO45926
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IFITM5 Antibody (PACO45926) |
| Antibody SKU: | PACO45926 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Interferon-induced transmembrane protein 5 protein (1-36AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO45926 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO45926 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Required for normal bone mineralization. |
| Synonyms: | Interferon-induced transmembrane protein 5 (Bone-restricted interferon-induced transmembrane protein-like protein) (BRIL) (Dispanin subfamily A member 1) (DSPA1), IFITM5 |
| UniProt Protein Function: | IFITM5: Plays a role in bone mineralization. Belongs to the CD225/Dispanin family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11p15.5Cellular Component: integral to plasma membraneBiological Process: bone mineralizationDisease: Osteogenesis Imperfecta, Type V |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012] |
| UniProt Code: | A6NNB3 |
| NCBI GenInfo Identifier: | 158705851 |
| NCBI Gene ID: | 387733 |
| NCBI Accession: | A6NNB3.1 |
| UniProt Secondary Accession: | A6NNB3 |
| UniProt Related Accession: | A6NNB3 |
| Molecular Weight: | 14,378 Da |
| NCBI Full Name: | Interferon-induced transmembrane protein 5 |
| NCBI Synonym Full Names: | interferon induced transmembrane protein 5 |
| NCBI Official Symbol: | IFITM5 |
| NCBI Official Synonym Symbols: | OI5; BRIL; DSPA1; Hrmp1; fragilis4 |
| NCBI Protein Information: | interferon-induced transmembrane protein 5 |
| UniProt Protein Name: | Interferon-induced transmembrane protein 5 |
| UniProt Synonym Protein Names: | Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Dispanin subfamily A member 1; DSPA1 |
| Protein Family: | Interferon-induced transmembrane protein |
| UniProt Gene Name: | IFITM5 |
| UniProt Entry Name: | IFM5_HUMAN |
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