Description
system_update_alt Datasheet
Product Name: | IDH1 Antibody |
Product Sku: | CPAB0231 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human IDH1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IDH1 protein 1-414 amino acids purified from Ecoli. |
Clone: | PAT25H10AT. |
Reactivity: | Human |
Applications: | ELISA, Flow Cytometry |
Purification Method: | IDH1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | Isocitrate Dehydrogenase is an enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. |
Synonyms: | Isocitrate dehydrogenase [NADP] cytoplasmic, EC 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase, IDH, NADP(+)-specific ICDH, IDP, PICD. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |