ICT1 Monoclonal Antibody [PAT1E9A] (CPAB0587)
![ICT1 Monoclonal Antibody [PAT1E9A] (CPAB0587)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58808/63990/ict1-monoclonal-antibody-pat1e9a-cpab0587__46661__14237.1706535224.jpg?c=1 "ICT1 Monoclonal Antibody [PAT1E9A] (CPAB0587)")
- SKU:
- CPAB0587
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT1E9A
- Applications:
- WB
- Applications:
- ELISA
![ICT1 Monoclonal Antibody [PAT1E9A] (CPAB0587)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58808/63990/ict1-monoclonal-antibody-pat1e9a-cpab0587__46661__14237.1706535224.jpg?c=1&imbypass=on "ICT1 Monoclonal Antibody [PAT1E9A] (CPAB0587)")
Description
system_update_alt Datasheet
| Product Name: | ICT1 Antibody |
| Product Sku: | CPAB0587 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human ICT1 mAb, clone PAT1E9A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ICT1 protein 3-26 amino acids purified from Ecoli. |
| Clone: | PAT1E9A. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | ICT1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | Immature Colon Carcinoma Transcript 1 (ICT1) functions as a codon-independent translation release factor that has lost all stop codon specificity and leads the termination of translation in mitochondrion in case of abortive elongation. The mature colon epithelium has 3 differentiated cell types which arise from a multipotent stem cell. ICT1 is involved in the hydrolysis of peptidyl-tRNAs which have been prematurely terminated and consequently in the recycling of stalled mitochondrial ribosomes. Digression from the normal maturation pathway by neoplastic transformation is assumed to originate in stem cells or their early descendants. |
| Synonyms: | DS-1, DS1, Peptidyl-tRNA hydrolase ICT1 mitochondrial, Digestion substraction 1, Immature colon carcinoma transcript 1 protein, ICT1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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