ICOS/CD278 Monoclonal Antibody
- SKU:
- CAB23995
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- FC
Description
| Product Name: | ICOS/CD278 Monoclonal Antibody |
| Product Code: | CAB23995 |
| Reactivity: | Mouse |
| Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62052 |
| Reactivity: | Mouse |
| Tested Applications: | WB, IF/ICC, FC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200, FC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Transfected CHO whole cell extracts. |
| Cellular Location: | Cell membrane |
Predicted to be involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Located in external side of plasma membrane. Is integral component of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 21-142 of mouse ICOS/CD278(NP_059508.2). |
| Sequence: | EINGS ADHRM FSFHN GGVQI SCKYP ETVQQ LKMRL FRERE VLCEL TKTKG SGNAV SIKNP MLCLY HLSNN SVSFF LNNPD SSQGS YYFCS LSIFD PPPFQ ERNLS GGYLH IYESQ LCCQL KL |
| Synonyms: | H4, CCLP, AILIM, CRP-1, Ly115 |
| Calculated MW: | 22kDa |
| Observed MW: | 22-35kDa |
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