ICOS/CD278 Monoclonal Antibody

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SKU:
CAB23995
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF
Applications:
FC

Description

Product Name:ICOS/CD278 Monoclonal Antibody
Product Code:CAB23995
Reactivity:Mouse
Applications:Western blotting, Immunofluorescence, Flow Cytometry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62052
Reactivity:Mouse
Tested Applications:WB, IF/ICC, FC, ELISA
Key Applications:Western blotting, Immunofluorescence, Flow Cytometry
Recommended Dilution:WB 1:1000-1:5000, IF/ICC 1:50-1:200, FC 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Transfected CHO whole cell extracts.
Cellular Location:Cell membrane

Predicted to be involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Located in external side of plasma membrane. Is integral component of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).

Immunogen:Recombinant fusion protein containing a sequence corresponding to aminoacids 21-142 of mouse ICOS/CD278(NP_059508.2).
Sequence:EINGS ADHRM FSFHN GGVQI SCKYP ETVQQ LKMRL FRERE VLCEL TKTKG SGNAV SIKNP MLCLY HLSNN SVSFF LNNPD SSQGS YYFCS LSIFD PPPFQ ERNLS GGYLH IYESQ LCCQL KL
Synonyms:H4, CCLP, AILIM, CRP-1, Ly115
Calculated MW:22kDa
Observed MW:22-35kDa
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