ICE1 Antibody (PACO47262)
- SKU:
- PACO47262
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ICE1 Antibody (PACO47262) |
| Antibody SKU: | PACO47262 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO47262 at dilution of 1:100. |
 | Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: ICE1 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 68 kDa. Observed band size: 68 kDa. |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO47262 at dilution of 1:100. |
| Background: | Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies. |
| Synonyms: | Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1), ICE1, KIAA0947 |
| UniProt Protein Function: | ICE1: protein of unknown function.Protein type: Unknown functionChromosomal Location of Human Ortholog: 5p15.32Cellular Component: Cajal body; nucleoplasm; transcription elongation factor complexMolecular Function: protein binding; protein homodimerization activityBiological Process: positive regulation of protein complex assembly; positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y2F5 |
| NCBI GenInfo Identifier: | 149363685 |
| NCBI Gene ID: | 23379 |
| NCBI Accession: | NP_056140.1 |
| UniProt Secondary Accession: | Q9Y2F5,Q68DE1, Q6ZT40, Q7L587, Q7Z3A9, Q9NTH9 |
| UniProt Related Accession: | Q9Y2F5 |
| Molecular Weight: | 247,891 Da |
| NCBI Full Name: | little elongation complex subunit 1 |
| NCBI Synonym Full Names: | interactor of little elongation complex ELL subunit 1 |
| NCBI Official Symbol: | ICE1 |
| NCBI Official Synonym Symbols: | KIAA0947 |
| NCBI Protein Information: | little elongation complex subunit 1 |
| UniProt Protein Name: | Little elongation complex subunit 1 |
| UniProt Synonym Protein Names: | Interactor of little elongator complex ELL subunit 1 |
| Protein Family: | Little elongation complex |
| UniProt Gene Name: | ICE1 |
| UniProt Entry Name: | ICE1_HUMAN |
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