IBA57 Antibody (PACO60092)
- SKU:
- PACO60092
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IBA57 Antibody (PACO60092) |
| Antibody SKU: | PACO60092 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Putative transferase CAF17, mitochondrial protein (286-356AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate, 293T whole cell lysate, HepG2 whole cell lysate, Mouse liver tissue. All lanes: IBA57 antibody at 4.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa. |
 | IHC image of PACO60092 diluted at 1:400 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO60092 diluted at 1:400 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. |
| Synonyms: | Putative transferase CAF17, mitochondrial (EC 2.1) (Iron-sulfur cluster assembly factor homolog), IBA57, C1orf69 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q5T440 |
| NCBI GenInfo Identifier: | 58197556 |
| NCBI Gene ID: | 200205 |
| NCBI Accession: | NP_001010867.1 |
| UniProt Secondary Accession: | Q5T440 |
| UniProt Related Accession: | Q5T440 |
| Molecular Weight: | 39 kDa |
| NCBI Full Name: | putative transferase CAF17, mitochondrial isoform 1 |
| NCBI Synonym Full Names: | iron-sulfur cluster assembly factor IBA57 |
| NCBI Official Symbol: | IBA57 |
| NCBI Official Synonym Symbols: | MMDS3; SPG74; C1orf69 |
| NCBI Protein Information: | putative transferase CAF17, mitochondrial |
| UniProt Protein Name: | Putative transferase CAF17, mitochondrial |
| UniProt Synonym Protein Names: | Iron-sulfur cluster assembly factor homolog |
| Protein Family: | |
| UniProt Gene Name: | IBA57 |
| UniProt Entry Name: | CAF17_HUMAN |
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