HYAL1 Monoclonal Antibody
- SKU:
- CAB23834
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | HYAL1 Monoclonal Antibody |
| Product Code: | CAB23834 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62100 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2 |
| Cellular Location: | Lysosome, Secreted |
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-435 of human HYAL1(NP_149349.2). |
| Sequence: | FRGPL LPNRP FTTVW NANTQ WCLER HGVDV DVSVF DVVAN PGQTF RGPDM TIFYS SQLGT YPYYT PTGEP VFGGL PQNAS LIAHL ARTFQ DILAA IPAPD FSGLA VIDWE AWRPR WAFNW DTKDI YRQRS RALVQ AQHPD WPAPQ VEAVA QDQFQ GAARA WMAGT LQLGR ALRPR GLWGF YGFPD CYNYD FLSPN YTGQC PSGIR AQNDQ LGWLW GQSRA LYPSI YMPAV LEGTG KSQMY VQHRV AEAFR VAVAA GDPNL PVLPY VQIFY DTTNH FLPLD ELEHS LGESA AQGAA GVVLW VSWEN TRTKE SCQAI KEYMD TTLGP FILNV TSGAL LCSQA LCSGH GRCVR RTSHP KALLL LNPAS FSIQL TPGGG PLSLR GALSL EDQAQ MAVEF KCRCY PGWQA PWCER KSMW |
| Synonyms: | HYAL1, HYAL-1, LUCA1, MPS9, NAT6, hyaluronidase-1 |
| Calculated MW: | 10kDa/19kDa/23kDa/27kDa/37kDa/45kDa/48kDa |
| Observed MW: | 60kDa |
Related Products
SPAM1 Monoclonal Antibody
OverviewProduct Name:SPAM1 Monoclonal AntibodyProduct Code:CAB22178Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
PMS2 Monoclonal Antibody
OverviewProduct Name:PMS2 Monoclonal AntibodyProduct Code:CAB22350Reactivity:HumanApplications:Western blotting
ACSL3 Monoclonal Antibody
OverviewProduct Name:ACSL3 Monoclonal AntibodyProduct Code:CAB22085Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
NeuroD1 Monoclonal Antibody
OverviewProduct Name:NeuroD1 Monoclonal AntibodyProduct Code:CAB12020Reactivity:MouseApplications:Western blotting<