HUNK Antibody (PACO20743)
- SKU:
- PACO20743
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | HUNK Antibody (PACO20743) |
| Antibody SKU: | PACO20743 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human HUNK |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20743(HUNK Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. |
| Synonyms: | hormonally up-regulated Neu-associated kinase |
| UniProt Protein Function: | HUNK: a protein kinase of the CAMKL family. Is developmentally regulated in a tissue-specific fashion. May contribute to changes in the mammary gland that occur during pregnancy in response to ovarian hormones. The active enzyme is localized in the nucleocytoplasm and the centrosome.Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); CAMK group; CAMKL family; HUNK subfamilyChromosomal Location of Human Ortholog: 21q22.1Cellular Component: cytoplasm; nucleusBiological Process: multicellular organismal development; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P57058 |
| NCBI GenInfo Identifier: | 9973393 |
| NCBI Gene ID: | 30811 |
| NCBI Accession: | P57058.1 |
| UniProt Secondary Accession: | P57058 |
| UniProt Related Accession: | P57058 |
| Molecular Weight: | 79,686 Da |
| NCBI Full Name: | Hormonally up-regulated neu tumor-associated kinase |
| NCBI Synonym Full Names: | hormonally up-regulated Neu-associated kinase |
| NCBI Official Symbol: | HUNK |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | hormonally up-regulated neu tumor-associated kinase |
| UniProt Protein Name: | Hormonally up-regulated neu tumor-associated kinase |
| UniProt Synonym Protein Names: | B19; Serine/threonine-protein kinase MAK-V |
| Protein Family: | Hormonally up-regulated neu tumor-associated kinase |
| UniProt Gene Name: | HUNK |
| UniProt Entry Name: | HUNK_HUMAN |
| Antibodies |
| HUNK Antibody (PACO04042) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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