Cell Cycle Recombinant Proteins

Human ZWINT Recombinant Protein (RPES3087)

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SKU:
RPES3087
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Cycle

Description

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Human ZWINT Recombinant Protein

ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.

Product Name:Human ZWINT Recombinant Protein (RPES3087)
Product Code:RPES3087
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT
Accession:O95229
Sequence:Met 1-Pro277
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human ZW10 Interactor is produced by our E.coli expression system and the target gene encoding Met1-Pro277 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:33.4 kDa
AP Mol Mass:36 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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