Human ZFAND6 (AN1-type zinc finger 6) ELISA Kit

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SKU:
HUFI01502
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q6FIF0
Sensitivity:
0.938mIU/ml
Range:
1.563-100mIU/ml
ELISA Type:
Sandwich
Synonyms:
ZFAND6, AN1-type zinc finger protein 6, HT032, AWP1, ZA20D3, Associated with PRK1 protein, Zinc finger A20 domain-containing protein 3
Reactivity:
Human
Research Area:
Cell Death

Description

Human ZFAND6 (AN1-type zinc finger 6) ELISA

ZFAND6 (Zinc Finger AN1-Type Containing 6) regulates the 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases the interaction between TRAF2 and RIPK1. TNF-alpha induced NF-kappa-B activation and apoptosis are regulated by ZFAND6. ZFAND6 is required for PTS1 target sequence-dependent protein import into peroxisomes, as well as PEX5 stability. Zellweger syndrome and peroxisome biogenesis disorder 1B are examples of diseases linked to ZFAND6. The ZFAND6 gene has a number of GO annotations that are concerned with polyubiquitin modification-dependent protein binding. ZFAND5 is a paralog of ZFAND6.

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