Human ZCCHC17 Recombinant Protein (RPPB5177)
- SKU:
- RPPB5177
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NP64
Description
| Product Name: | Human ZCCHC17 Recombinant Protein |
| Product Code: | RPPB5177 |
| Size: | 10µg |
| Species: | Human |
| Target: | ZCCHC17 |
| Synonyms: | Zinc finger CCHC domain containing 17, PS1D, pNO40, HSPC251, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, RP11-266K22.1, Nucleolar protein of 40 kDa, PS1D protein. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The ZCCHC17 protein solution (0.25mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 100mM NaCl, 2mM DTT, 0.1mM PMSF and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNSGRPE TMENLPALYT IFQGEVAMVT DYGAFIKIPG CRKQGLVHRT HMSSCRVDKP SEIVDVGDKV WVKLIGREMK NDRIKVSLSM KVVNQGTGKD LDPNNVIIEQ EERRRRSFQD YTGQKITLEA VLNTTCKKCG CKGHFAKDCF MQPGGTKYSL IPDEEEEKEE AKSAEFEKPD PTRNPSRKRK KEKKKKKHRD RKSSDSDSSD SESDTGKRAR HTSKDSKAAK KKKKKKKHKK KHKE |
ZCCHC17 protein interacts with PNN and associates with the 60S ribosomal subunit. Universally expressed, ZCCHC17 is localizing to the�nucleolus, and takes part in ribosome maturation and biogenesis.
ZCCHC17 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 264 amino acids (1-241a.a.) and having a molecular mass of 30.0 kDa (Molecular weight on SDS-PAGE will appear higher). ZCCHC17 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ZCCHC17: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; Ribosomal; RNA-binding Chromosomal Location of Human Ortholog: 1p35.2 Cellular Component: intermediate filament cytoskeleton; intracellular membrane-bound organelle; nucleolus; ribonucleoprotein complex; nucleus Molecular Function:protein binding; zinc ion binding |
| UniProt Code: | Q9NP64 |
| NCBI GenInfo Identifier: | 543173111 |
| NCBI Gene ID: | 51538 |
| NCBI Accession: | NP_001269495.1 |
| UniProt Related Accession: | Q9NP64 |
| Molecular Weight: | |
| NCBI Full Name: | nucleolar protein of 40 kDa isoform a |
| NCBI Synonym Full Names: | zinc finger CCHC-type containing 17 |
| NCBI Official Symbol: | ZCCHC17�� |
| NCBI Official Synonym Symbols: | PS1D; pNO40; HSPC251�� |
| NCBI Protein Information: | nucleolar protein of 40 kDa |
| UniProt Protein Name: | Nucleolar protein of 40 kDa |
| UniProt Synonym Protein Names: | Pnn-interacting nucleolar protein; Putative S1 RNA-binding domain protein; PS1D protein; Zinc finger CCHC domain-containing protein 17 |
| UniProt Gene Name: | ZCCHC17�� |
| UniProt Entry Name: | NO40_HUMAN |
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