Human YKL-40/CHI3L1 Polyclonal Antibody
- SKU:
- CAB22029
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Human YKL-40/CHI3L1 Polyclonal Antibody |
| Product Code: | CAB22029 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1, A-204 |
| Cellular Location: | cytoplasm, endoplasmic reticulum, extracellular exosome, extracellular region, extracellular space, perinuclear region of cytoplasm |
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-383 of human YKL-40/CHI3L1 (NP_001267.2). |
| Sequence: | YKLVC YYTSW SQYRE GDGSC FPDAL DRFLC THIIY SFANI SNDHI DTWEW NDVTL YGMLN TLKNR NPNLK TLLSV GGWNF GSQRF SKIAS NTQSR RTFIK SVPPF LRTHG FDGLD LAWLY PGRRD KQHFT TLIKE MKAEF IKEAQ PGKKQ LLLSA ALSAG KVTID SSYDI AKISQ HLDFI SIMTY DFHGA WRGTT GHHSP LFRGQ EDASP DRFSN TDYAV GYMLR LGAPA SKLVM GIPTF GRSFT LASSE TGVGA PISGP GIPGR FTKEA GTLAY YEICD FLRGA TVHRI LGQQV PYATK GNQWV GYDDQ ESVKS KVQYL KDRQL AGAMV WALDL DDFQG SFCGQ DLRFP LTNAI KDALA AT |
| Synonyms: | GP39, ASRT7, GP-39, YK-40, YKL40, CGP-39, YKL-40, YYL-40, HC-gp39, HCGP-3P, hCGP-39 |
| Calculated MW: | 43kDa |
| Observed MW: | 43kDa |
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