Human XCR1 Full-Length Bioactive Membrane Protein (HDFP101)

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SKU:
HDFP101
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P46094

Description

system_update_altDatasheet
Product nameHuman XCR1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP101
Product CategoryFull Length Transmembrane Proteins
Target:XCR1
Uniprot:P46094
Description:Human XCR1 full length protein-synthetic nanodisc
Molecular Weight:The human full length XCR1 protein has a MW of 38.3 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:CCXCR1; GPR5
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020]
Delivery:3-4 weeks
UsageResearch use only
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