Human VWFCP/ADAMTS13 Recombinant Protein (His tag)

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Mol Mass:	30.36 kDa
AP Mol Mass:	31 kDa
Tag:	N-His
Purity:	> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:	Please contact us for more information.
Bio Activity:	Testing in progress

Sequence:	Thr 1151-Thr 1427
Accession:	Q76LX8
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation.Zinc and calcium ions cooperatively modulate enzyme activity. The cleavage of the pro-domain is not required for protease activity. Dependence on calcium for proteolytic activity is mediated by the high affinity site.

Product Name:	Human VWFCP/ADAMTS13 Recombinant Protein (His tag)
Product Code:	RPES5495
Size:	20µg
Species:	Human
Expression Host:	E.coli
Synonyms:	ADAM-TS 13, ADAMTS 13, ATS13, C9orf8, TTP, Von Willebrand factor cleaving protease, vWF CP, vWF-cleaving protease