Human VSTM1 Recombinant Protein (RPES2710)
- SKU:
- RPES2710
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human VSTM1 Recombinant Protein
V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
| Product Name: | Human VSTM1 Recombinant Protein (RPES2710) |
| Product Code: | RPES2710 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | V-set and transmembrane domain-containing protein 1,SIRL-1,Signal inhibitory receptor on leukocytes-1,VSTM1 |
| Accession: | Q6UX27 |
| Sequence: | Tyr17-Thr135 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human V-set and Transmembrane Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Tyr17-Thr135 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 14.6 kDa |
| AP Mol Mass: | 25-35 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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