Signal Transduction Recombinant Proteins

Human Vitamin D-Binding Recombinant Protein (RPES2584)

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SKU:
RPES2584
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

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Human Vitamin D-Binding Recombinant Protein

Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

Product Name:Human Vitamin D-Binding Recombinant Protein (RPES2584)
Product Code:RPES2584
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Vitamin D-Binding Protein, DBP, VDB, Gc-Globulin, Group-Specific Component, GC
Accession:P02774
Sequence:Leu17-Leu474
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Vitamin D-Binding Protein is produced by our Mammalian expression system and the target gene encoding Leu17-Leu474 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:52.3 kDa
AP Mol Mass:53 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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