Human VEGF-B/VEGFB Recombinant Protein (RPES3768)

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SKU:
RPES3768
Product Type:
Recombinant Protein
Species:
Human

Description

system_update_altDatasheet

Human VEGF-B/VEGFB Recombinant Protein

VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.

Product Name:Human VEGF-B/VEGFB Recombinant Protein (RPES3768)
Product Code:RPES3768
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Vascular endothelial growth factor B,VEGF-B,VEGF-related factor,VRF
Accession:P49765
Sequence:Pro22-Ala207
Fusion tag:N-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human VEGFB is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:45.7 kDa
AP Mol Mass:40&60 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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