Human Uroplakin-2/UPK2 Recombinant Protein (RPES2312)
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- SKU:
- RPES2312
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Uroplakin-2/UPK2 Recombinant Protein
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
| Product Name: | Human Uroplakin-2/UPK2 Recombinant Protein (RPES2312) |
| Product Code: | RPES2312 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Uroplakin-2, UP2, Uroplakin II, UPII, UPK2 |
| Accession: | O00526 |
| Sequence: | Asp26-Gly155 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Uroplakin-2 is produced by our Mammalian expression system and the target gene encoding Asp26-Gly155 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 14.8 kDa |
| AP Mol Mass: | 27 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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