Description
| Product Name: | Human UQCRH Recombinant Protein |
| Product Code: | RPPB5090 |
| Size: | 20µg |
| Species: | Human |
| Target: | UQCRH |
| Synonyms: | Cytochrome c1 non-heme 11 kDa protein, Ubiquinol-cytochrome c reductase complex 11 kDa protein, UQCRH, Ubiquinol-Cytochrome C Reductase Hinge Protein, Complex III Subunit VIII, Complex III Subunit 6, Mitochondrial Hinge Protein, Ubiquinol-Cytochrome C Reductase, QCR6, UQCR8, Cytochrome B-C1 Complex Subunit 6 Mitochondrial, Ubiquinol-Cytochrome C Reductase Complex III Subunit VIII. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | UQCRH protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSGDPEEEE EEEEELVDPL TTVREQCEQL EKCVKARERL ELCDERVSSR SHTEEDCTEE LFDFLHARDH CVAHKLFNNL K |
Ubiquinol-Cytochrome C Reductase Hinge Protein (UQCRH) is a member of the UQCRH/QCR6 family. UQCRH is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The UQCRH protein mediates formation of the complex between cytochromes c and c1.
UQCRH Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (14-91 a.a) and having a molecular mass of 11.6kDa.UQCRH is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | UQCRH: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family.Protein type: Oxidoreductase; EC 1.10.2.2; Energy Metabolism - oxidative phosphorylation; MitochondrialChromosomal Location of Human Ortholog: 1p34.1Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain; mitochondrionMolecular Function: protein binding; ubiquinol-cytochrome-c reductase activityBiological Process: aerobic respiration; mitochondrial electron transport, ubiquinol to cytochrome c; oxidative phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P07919 |
| NCBI GenInfo Identifier: | 62202498 |
| NCBI Gene ID: | 7388 |
| NCBI Accession: | AAH93060.1 |
| UniProt Secondary Accession: | P07919,Q5TDF6, Q6LDB8, Q9BQ91, B2R4V9, D3DQ18 |
| UniProt Related Accession: | P07919 |
| Molecular Weight: | 10,739 Da |
| NCBI Full Name: | UQCRH protein |
| NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase hinge protein |
| NCBI Official Symbol: | UQCRH�� |
| NCBI Official Synonym Symbols: | QCR6; UQCR8�� |
| NCBI Protein Information: | cytochrome b-c1 complex subunit 6, mitochondrial |
| UniProt Protein Name: | Cytochrome b-c1 complex subunit 6, mitochondrial |
| UniProt Synonym Protein Names: | Complex III subunit 6; Complex III subunit VIII; Cytochrome c1 non-heme 11 kDa protein; Mitochondrial hinge protein; Ubiquinol-cytochrome c reductase complex 11 kDa protein |
| Protein Family: | Probable cytochrome b-c1 complex |
| UniProt Gene Name: | UQCRH�� |
| UniProt Entry Name: | QCR6_HUMAN |