Enzymes Recombinant Proteins

Human UFC1 Recombinant Protein (RPPB2398)

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RPPB2398

Description

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Product Name:Human UFC1 Recombinant Protein
Product Code:RPPB2398
Size:20µg
Species:Human
Target:UFC1
Synonyms:Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1, UFC1, CGI-126, HSPC155.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:UFC1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability:UFC1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD NDWFRLESNK EGTRWFGKCW YIHDLLKYEF DIEFDIPITY PTTAPEIAVP ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEI PDLIQKGVIQ HKEKCNQ

UFC1 is a member of the ubiquitin-conjugating enzyme family. UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1. UFM1 is activated by UBA5 (a novel E1-like enzyme) by forming a high-energy thioester bond. Activated UFM1 is subsequently transferred to its cognate E2-like enzyme, UFC1, in a similar thioester linkage.

UFC1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 187 amino acids (1-167 a.a.) and having a molecular mass of 21.6kDa.UFC1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
NCBI Summary:UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Mar 2008]
UniProt Code:Q9Y3C8
NCBI GenInfo Identifier:156416000
NCBI Gene ID:51506
NCBI Accession:NP_057490
UniProt Secondary Accession:Q9Y3C8,Q549X0, Q5VTX1, Q9BS96, Q9P009, A8K9R1, D3DVF9
UniProt Related Accession:Q9Y3C8
Molecular Weight:21.6 kDa (187aa), confirmed by MALDI-TOF
NCBI Full Name:ubiquitin-fold modifier-conjugating enzyme 1
NCBI Synonym Full Names:ubiquitin-fold modifier conjugating enzyme 1
NCBI Official Symbol:UFC1��
NCBI Official Synonym Symbols:HSPC155��
NCBI Protein Information:ubiquitin-fold modifier-conjugating enzyme 1
UniProt Protein Name:Ubiquitin-fold modifier-conjugating enzyme 1
UniProt Gene Name:UFC1��
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9Y3C8
Research Area:
Enzymes
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