Signal Transduction Recombinant Proteins

Human UCHL3/UCH-L3 Recombinant Protein (RPES1881)

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SKU:
RPES1881
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Signal Transduction

Description

system_update_altDatasheet

Human UCHL3/UCH-L3 Recombinant Protein

Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.

Product Name:Human UCHL3/UCH-L3 Recombinant Protein (RPES1881)
Product Code:RPES1881
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3, UCH-L3, Ubiquitin Thioesterase L3, UCHL3
Accession:P15374
Sequence:Met 1-Ala230
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3 is produced by our E.coli expression system and the target gene encoding Met1-Ala230 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:27.3 kDa
AP Mol Mass:25 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 50mM TrisHCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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system_update_altDatasheetRat UCHL3/UCH-L3 Recombinant Protein Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein