Cell Cycle Recombinant Proteins

Human UBE2S Recombinant Protein (RPES2126)

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RPES2126

Description

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Human UBE2S Recombinant Protein

Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

Product Name:Human UBE2S Recombinant Protein (RPES2126)
Product Code:RPES2126
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin-Conjugating Enzyme E2 S, E2-EPF, Ubiquitin Carrier Protein S, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, UBE2S, E2EPF
Accession:Q16763
Sequence:Met 1-Leu222
Fusion tag:N-GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ubiquitin-Conjugating Enzyme E2 S is produced by our E.coli expression system and the target gene encoding Met1-Leu222 is expressed with a GST tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:50.1 kDa
AP Mol Mass:50 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Cycle
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